Question: How To Decide If The Deference Is Significant
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Du, Jianguang • 380 wrote:
Dear All,
I am looking for the deferential splicing events between cell types. I
have run the Cuffdiff and I am going through the output file "splicing
differential expression testing". I have read the documentation and
protocols about how Cuffdiff test for differential expression and
regulation. However although I know the changes in relative abundance
are quantified by the square root of the Jensen-Shannon divergence, I
still could not understand the concept of it (unfortunately I am not
good at math and statistics). Is there any way to convert "the square
root of the Jensen-Shannon divergence" into "fold of diference"? How
much of "the square root of the Jensen-Shannon divergence" equals to 2
fold of difference?
Thanks.
Jianguang